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OpiateAddictionRx WORLD NEWS
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The OpiateAddictionRx.info ENewsletter
August 2006

IN THIS ISSUE...
  • OUR BLOG (share your opinions)
  • HUNGARY: Methadone Treatment - A Long Way to Go
  • ISRAEL: Retention in Methadone Maintenance (MM) 74.4% After One Year
  • IRAN: Methadone Manufacturing to Launch
  • USA: NIDA- Drug Addiction “a Brain Disease"
  • USA:"Methadone Clinic Wins"
  • CHINA, HONG KONG, INDONESIA, IRAN, LITHUANIA, POLAND: Substitution Treatment Update
  • HEROIN TRIALS & SUPERVISED INJECTION SITES:
    - Review of Available Evidence
    - Fostering Knowledge, but Also Misunderstanding
    - Vancouver’s Supervised Injection Site at at Risk
    - Five Years with Medically Supervised Injection in Australia

  • HUNGARY: Methadone Treatment - A Long Way to Go

    The journal Psychiatric Services (June 2006) has an article by Gerevich et al on “degrees of sociocultural resistance” to methadone. It concludes with the hope that the country’s admission to the European Union will “have a favorable influence on the governmental resistance to opioid substitution treatment and to the professional legitimization of methadone maintenance . . . “ Clearly there’s a long way to go. The article notes that in 2005 roughly 400 health care organizations were treating drug users, but 88% do not deal with methadone at all and 8% use it only for detoxification. A mere 4% of all addiction treatment providers in Hungary offer methadone maintenance.


    ISRAEL: Retention in Methadone Maintenance (MM) 74.4% After One Year

    A report of 10 years of experience with MM in Israel indicates very high retention, cessation of heroin use by 66% over the course of the first 12 months, and a net decrease in cocaine use of over 60%. (Peles et al. Drug and Alc Dep 82(2006) 211-217)


    IRAN: Methadone Manufacturing to Launch

    The Islamic Republic News Agency (July 29) reports that methadone production is about to be launched by two private pharmaceutical companies. Noting that "...treatment of addiction by methadone is a globally-accepted and effective method," the deputy health minister for food and drugs stated that the country needs "four to five times more than the amount currently imported."


    USA: NIDA- Drug Addiction “a Brain Disease"

    Medicines such as methadone and buprenorphine, shown to help normalize brain functions and should be made available”(July, 2006). These key principles are the underpinnings of what has been described (Seattle Times, July 25), as NIDA’s “first report aimed at improving how the criminal justice system deals with drug addicts.”


    USA:"Methadone Clinic Wins"

    The above is the headline of Baltimore Sun news story that ran Aug 9th. In this field, and specifically when it comes to NIMBY, headlines don't get much better than that!

    After a four year legal battle in federal court against the government of Baltimore County, MD (different than Baltimore City), a Fourth Circuit U.S. District Court and jury found that the County discriminated against A Helping Hand methadone program and its patients when it made a zoning ordinance that would have restricted the (already licensed) methadone clinic from operating.

    The County was found to have violated the Americans With Disabilities Act (ADA) and the Due Process Clause of the 14th Amendment of the U.S. Constitution when it enacted and tried to enforce a law prohibiting the methadone clinic from operating within 750 feet of a residence.

    The owner of the clinic, Joel Prell, and three patients brought the lawsuit to federal court and testified. ICAAT's director, Dr. Robert Newman, was their expert witness. They were represented by a Washington DC law firm, Steptoe and Johnson, and the American Civil Liberties Union joined the case; the attorneys as well as Dr. Newman acted pro bono.

    ICAAT congratulates Mr. Prell and the patients who showed great strength in standing up for the right to get methadone maintenance treatment where it was needed, and all those who helped them win this legal victory.


    CHINA, HONG KONG, INDONESIA, IRAN, LITHUANIA, POLAND: Substitution Treatment Update

    Summary (in German) was prepared by Ingo Michels ingoiljamichels@gmails.com

    CHINA (Prof. Q. Lu): first 8 MMT clinics opened at the beginning 0f 2004; end of March 2006 there were about 128 and the goal is 300 by the end of the year. “The results of methadone treatment are compelling.” Health and quality of life both improved markedly; depression decreased; HIV and hepatitis rates stabilized. Risky sexual behaviour increased, but criminality essentially stopped and the employment rate rose from 25% to 31% [not clear what time period]. Three-month retention rate was 97% [!!] and at the end of 6 months 85%. Average methadone dosage after 6 months was 49mg/day.

    HONG KONG (Prof. Char-Nie C Hen): 30 year history of substitution treatment, whose objective is to ensure an easily accessible, legal, medically safe alternative to illegal opiate use, to maintain contact with patients, reduce anti-social and criminal activity and assist patients to lead normal and productive lives. Patient visits to HK methadone clinics have averaged about 2.5 million per year for the past 15 years. Approximately 2/3 of the estimated 14,000 addicts are in treatment. Harm reduction outcomes improved markedly when methadone dosages were raised. HIV rates among addicts in HK have consistently been extremely low.

    INDONESIA (Dr. Mardiati): Estimated total heroin addicted population 120,000 to 196,000. 44% of the new HIV positive cases were drug users; 70% of heroin consumers are under age 25. First methadone clinics opened in Jakarta and Bali in Jan- Feb 2003; Training has been provided to 312 physicians – mostly in private practice. Only 2% of the costs of methadone treatment are paid by the Government. Today there are 330 patients in Jakarta (300 in one clinic), and 330 in Bali; about 50 elsewhere in the country [NOTE estimated opiate dependent population, above]. 60% of patients are HIV positive.

    IRAN (Dr. Mokri): Methadone is generally in tablet form and there is hardly any psychosocial support; there’s a general sense that methadone alone is sufficient. Naltrexone is also available, but retention is very low and relapse after treatment almost 100%. It’s the experience of the University clinic in Tehran that methadone is equally effective in treating heroin-dependent as opium-dependent patients. Mokri advocates multi-modal treatment availability – including buprenorphine, which is provided at the University clinic and has retention of about 65%; buprenorphine patients come from better social settings and pay their own way – about $US 15 per month. Mokri also advocates maximum utilization of private medical care providers.

    LITHUANIA (Dr. Subata): HIV prevalence per 100,000 people is 28.1 in Lithuania, 112.9 in Latvia and 272.2 in Estonia and 470.0 in the Kaliningrad district. In January 2006 in Lithuania there were 436 patients being treated in 4 specialty centers and 8 public health facilities; by comparison there’s only one center in Latvia providing substitution treatment and 2 in Estonia [Russia outlaws substitution medications]. The methadone in these countries comes from Denmark and costs about 1 Euro ($US 1.28) per 100 mg.

    POLAND (Drs. Habrat and Moskalewicz): estimated addicts 35,000-40,000, of whom 5-7,000 come into contact with the medical care system each year. There’s high mortality. “Despite positive substitution treatment outcomes there are only about 700 clients being treated in 12 facilities.” Admission criteria are high: at least 18 years old, 3 failed drug- free treatments or medical indications (e.g., HIV/AIDS). Psychosocial support is offered and group meetings are mandatory.

    COMMENTS BY DR. ALEX WODAK (Australia): two fundamental aspects of a response to the problem/threat of HIV-AIDS are critical – it has to be comprehensive and it has to be very rapid! To achieve this total involvement of private as well as public health care providers is key.

    SUMMARY BY VLADIMIR POZNYAK OF WHO: short-term plans for methadone treatment that ensure care for only a few months without sustainability are unethical. Continued availability must be guaranteed. Disaster-planning is also imperative – e.g., in areas subject to frequent natural catastrophes. Minimal quality standards should be adhered to. And finally, there must be better coordination between security and health authorities: “they must speak the same language.”


    HEROIN TRIALS & SUPERVISED INJECTION SITES:
    - Review of Available Evidence
    - Fostering Knowledge, but Also Misunderstanding
    - Vancouver’s Supervised Injection Site at at Risk
    - Five Years with Medically Supervised Injection in Australia

    HEROIN “TRIALS” Review of Available Evidence- First an editorial comment, it should be noted that certain conclusions are so self-evident as to merit acceptance without a host of scientific studies involving randomization, double-blind technique, etc. We hope sophisticated readers will forgive this simplistic statement; in our defense we might point to an analogy: one accepts the life- saving role of parachutes, even without fancy studies and "statistically significant" outcomes. Having said that, it’s obviously essential to be familiar with such scientific data that do in fact exist and comprehensive and authoritative reviews of the evidence are available

    HEROIN TRIALS: Fostering Knowledge, but Also Misunderstanding - The trials of Switzerland, Netherlands, Germany etc. are to be applauded for demonstrating that heroin maintenance is feasible and effective for many. But the methodology also carries with it a downside (more)

    Vancouver’s Supervised Injection Site at Risk - The Canadian government is about to make a decision that will affect the future of North America’s first Supervised Injection Site in Vancouver. The Vancouver facility, Insite, opened in Sept. 2003 and Vancouver Coastal Health received a three-year scientific research exemption under the Canadian Controlled Drug and Substances Act allowing it to have illicit drugs in the facility for research purposes.

    Now, that exemption is up for renewal, and the government’s decision will determine whether this groundbreaking facility continues to operate. Right now, that future is very much in doubt. Insite is seeking your assistance.(click here)

    Five Years with Medically Supervised Injection in Australia-The bottom line, according to our colleague Andrew Byrne: 200-300 injections each day, not a single death, strong support from local residents, businesses and "most police." For more on the service click http://www.sydn eymsic.com/.


    OUR BLOG (share your opinions)

    Call for Common Voice Supporting all forms of Maintenance Treatment:

    Buprenorphine: Good News and Bad

    Vincent P. Dole, MD, Dies at 93 (Aug 2, 2006)

    METHADONE PACKAGE INSERT: use as directed, (but make sure your heirs have a good malpractice lawyer available)

    To view the entire blog click here

    16th INTERNATIONAL AIDS CONFERENCE Follow the Conference Blog

    Law and Health Initiative Presents Materials
    Upcoming Events...

    AIDS 2006 // SIDA 2006
    August 13 - 18 2006
    Toronto, Canada

    The 9th ENDIPP conference
    "From the Principle of Equivalence to the Practice of Care: Bridging the Gap"
    October 5-7, 2006
    Ljubljana-Slovenia

    European Opiate Addiction Treatment Association & Slovak Professional Society for Dependencies on Psychoactive Substances Present Europad 7
    October 6-8, 2006, Bratislava

    For the Complete Calendar of Events



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