Malaysia: Expanding a Successful Pilot MMT Program
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The Malaysian government starting treating IDUs
with
methadone in October 2005. At a recent conference
on drug addiction, the government reported high
retention rates in their pilot program and announced
they intend to scale up treatment substantially.
Additionally, The Malaysian Aids Foundation (MAF)
has added its support for the continued prescribing
of methadone to IDUs. MAF chair Prof Dr Adeeba
Kamarulzaman said this week in a news
interview, "We give our 100 per cent support to the
Methadone project...it is very effective. At least it
can reduce the number of deaths due to drug abuse."
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UNAIDS: Executive Director Lauds China AIDS Policy
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Peter Piot, the executive director, notes that China
is a land of contrasts. On a recent visit to China, he
observed, "Frankly, two years ago I could not have
dreamt that there would be close to 300 methadone-
providing clinics for injecting drug users across the
country." He also noted, however, "...a mismatch
between high-level policy and enforcement on the
ground. He said China's public security organs, which
have in the past harassed and detained AIDS
activists, must lay off." Full story: Click Here
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Clinical Studies: Overview of Methadone Maintenance (MMT) Status and Efficacy
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The recently published article states that there are
1,080 MMT programs in US with estimated 215,667
patients enrolled. It notes, “Methadone relieves the
cravings associated with heroin use., Craving is a
major relapse trigger. Properly prescribed
methadone is not intoxicating or sedating, and its
use
does not interfere with normal activities of daily
living. The ability to drive an automobile or operate
machinery is not impaired by the use of properly
prescribed methadone.” As for efficacy: “Studies
have shown MMT significantly lowers illicit opiate
drug
use, reduces crime and enhances social productivity.”
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Hong Kong: Drug Abuse Data
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This website (which can be found by cutting and
pasting this address into the browser after the
http://www 202.64.76.168/en/enquiry.asp) is an
extraordinarily user-friendly, customized,
statistical analysis of drug abuse. It is available from
the Central Registry of Drug Abuse, Hong Kong.
The Registry has been collecting data consistently
for
exactly 30 years (first report published in September,
1976). It is a unique resource for studying trends in
drug use (and drug users) over time.
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USA: Community Opposition to Methadone Clinics Never Ending
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In just 48 hours stories appeared concerning
community opposition to establishment of methadone
treatment facilities in Baltimore, Bluefield (West
Virginia), Cherryfield (Maine) and Fort Payne
(Alabama).
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Austria: A Call for More "Substitution" Treatment
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A call for more treatment with medication such as
methadone, buprenorphine and slow-release
morphine. At a press conference on the 29th of
August addiction experts called for more opioid
agonist maintenance treatment above all else in the
fight against drug use. Professor Dr. Gabriele Fischer
of the University Clinic of Vienna, along with the
leadership of the Austrian Association for Psychiatry
and Psychotherapy, noted the critically important
role that "substitution" treatment can and must play
to reduce illegal drug use, lower mortality rates and
lessen spread of infectious diseases such as AIDS
and hepatitis. Currently only about 10% of the
roughly 50-70,000 opiate-dependent Austrians
receive such treatment.
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Clinical Study: Buprenorphine-Naloxone Administration
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Dr. Fiellin and co-authors report results of
buprenorphine-naloxone administration with varying
counseling intensity and number of weekly visits
(NEJM vol 355, 2006). Of 497 individuals “assessed
for eligibility,” 67% did not meet inclusion criteria or
failed to complete induction; inevitably, it calls into
question how representative the results can be, and
just how and to whom they can be extrapolated.
As for the reported findings for the remaining one-
third drug users that were assessed, 52-61% were
lost to follow-up at 24 weeks. This compares to
42%
drop-out rate at six months in Fudala's buprenorphine
study (NEJM vol 349, 2003) and 41% in a study by
Stein (J Gen Int Med vol 20, 2005). As for
effectiveness data beyond retention per se, 56-60%
of urine toxicologies in the Fiellin study were positive.
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